Prostate IMRT Guidelines

RTOG protocols: 0126, 0415, 0621,

also MDASKM, postop, high risk, low risk

 

from Practical Essentials of Intensity Modulated Radiation Therapy, second edition, ed K.S. Clifford Chao

Target Volume Delineation

  • CTV1 (low risk) = prostate +/- proximal seminal vesicles (74Gy)
  • CTV1 (intermediate risk) = prostate + proximal seminal vesicles (76-78Gy) / CTV2 = distal seminal vesicles (56Gy)
  • CTV1 (high risk) = prostate, gross extracapsular disease and proximal seminal vesicles (76-78Gy) CTV2 = distal sem ves and periprostatic nodes (56Gy)
  • PTV (if daily imaging) 5mm posterior and 8 mm all other (if less rigorous imaging then 1.1 cm) (PTV should get 95% of prescription dose)
Suggested Target and Normal Tissue Dose
  • Rectum: V65 less than or equal to 17% and V40 no more than 35%
  • Bladder: V65 at 25% and V40 at 35%
  • Femoral Heads v50 below 10%
  • on axial cuts the full rectum less than 50% IDL and less than half the 90% IDL

V65= volume receiving 65Gy