SWOG 8797/ GOG 109 Trial

Trial randomized 243 women with high risk cervical cancer (IA2, IB, IIA with node mets found at RH-PPLND to either postOp  radiation alone or Radiation plus chemotherapy (5FU infusion plus Platinol q 3w for four cycles) and show significant improvement in progression-free four year survival ( 63% to 80%) and over-all four year survival (71% versus 80%)

5 Year Survival Results 5 Year Survival Results by Therapy and Number of Nodes Involved
Nodes Radiation Radiation/Chemotherapy
1 + 79% 83%
2 or more + 55% 75%

SGO 2004 Meeting/ Oncology-Times/ 4-10-04