stomach.gif (11368 bytes)
Stage and Survival with Gastric Cancer

NCDB Survival Data (Cancer 199780:2333)
Stage 5 Year Survival
Ia 71%
Ib 56%
II 37%
IIIa 18%
IIIb 11%
IV 5%

 

SEER Stage Incidence (from the ACS)
Stage White Black
Local 20% 19%
Regional 30% 20%
Distant 35% 36%

SEER Survival
Stage White Black
All 19% 22%
Local 56% 56%
Regional 19% 26%
Distant 2% 3%
 
Stage Information

The American Joint Committee on Cancer (AJCC) has designated staging by TNM classification.TNM definitions

Primary tumor (T)

TX: Primary tumor cannot be assessed
T0: No evidence of primary tumor
Tis: Carcinoma in situ: intraepithelial tumor without invasion of the lamina propria
T1: Tumor invades lamina propria or submucosa
T2: Tumor invades the muscularis propria or the subserosa*
T3: Tumor penetrates the serosa (visceral peritoneum) without invading adjacent structures**,***
T4: Tumor invades adjacent structures***

*Note: A tumor may penetrate the muscularis propria with extension into the gastrocolic or gastrohepatic ligaments or into the greater or lesser omentum
without perforation of the visceral peritoneum covering these structures. In this case, the tumor is classified T2. If there is perforation of thevisceral peritoneum covering the gastric ligaments or omentum, the tumor should be classified T3.

**Note: The adjacent structures of the stomach include the spleen, transverse

colon, liver, diaphragm, pancreas, abdominal wall, adrenal gland, kidney,small intestine, and retroperitoneum.

***Note: Intramural extension to the duodenum or esophagus is classified by the depth of greatest invasion in any of these sites, including stomach.

Regional lymph nodes (N)

The regional lymph nodes are the perigastric nodes, found along the lesser and greater curvatures, and the nodes located along the left gastric, common hepatic, splenic, and celiac arteries. For pN, a regional lymphadenectomy specimen will ordinarily contain at least 15 lymph nodes. Involvement of other intra-abdominal lymph nodes, such as the hepatoduodenal, retropancreatic, mesenteric, and para-aortic, is classified as distant metastasis.

NX: Regional lymph node(s) cannot be assessed
N0: No regional lymph node metastasis
N1: Metastasis in 1 to 6 regional lymph nodes
N2: Metastasis in 7 to 15 regional lymph nodes
N3: Metastasis in more than 15 regional lymph nodes

Distant metastasis (M)

MX: Distant metastasis cannot be assessed
M0: No distant metastasis
M1: Distant metastasis

AJCC stage groupings
Stage 0:        Tis, N0, M0
Stage IA:      T1, N0, M0
Stage IB:      T1, N1, M0,     T2, N0, M0
Stage II:       T1, N2, M0,     T2, N1, M0,      T3, N0, M0
Stage IIIA:   T2, N2, M0,     T3, N1, M0,        T4, N0, M0
Stage IIIB:   T3, N2, M0
Stage IV:     T4, N1, M0,   T1, N3, M0,   T2, N3, M0,    T3, N3, M0,    T4, N2, M0,    T4, N3, M0,   Any T, Any N, M1