|
Tumor
Characteristics |
Dose
Fractionation |
TDF |
|
MGH |
|
<1 cm tumor; debilitated patient |
20–24 Gy in 1 fraction |
— |
|
<2 cm tumor |
45 Gy in 5–9 fractions |
122—131 |
|
2–4 cm or cosmetic concerns |
52 Gy in 13 fractions |
125 |
|
>4 cm tumor |
60 Gy in 20 fractions |
123 |
|
|
64 Gy in 25 fractions |
116 |
|
MDACC |
|
≤1 cm; elderly patient |
40 Gy in 8 fractions |
125 |
|
>1–2 cm in elderly or ≤2 cm in young patient |
50 Gy in 15–20 fractions |
108–127 |
|
Large fields needing good cosmesis |
60 Gy in 30 fractions |
115 |
|
Large, infiltrating tumors |
64 to 66 Gy in 32–33 fractions |
122–126
|
|
University of Florida |
|
Large, untreated + bone/cartilage invasion or large,
recurrent |
65 Gy in 35 fractions |
115 |
|
Large, untreated + minimal or suspected bone/cartilage
invasion |
60 Gy in 34 fractions |
112 |
|
Moderate-to-large inner canthus, eyelid, nasal, pinna (20–30
cm2) |
55 Gy in 30 fractions |
99 |
|
Small, thin (<1.5 cm) eye, nose, ear (10 cm2) |
50 Gy in 20 fractions |
108 |
|
Moderate or postoperative cut-through on free skin |
45 Gy in 15 fractions |
107 |
|
Small (1 cm) on free skin |
40 Gy in 10 fractions |
111 |
|
|
30 Gy in 5 fractions |
103 |
|
Cosmesis not important |
40 Gy in 10 fractions |
111 |
|
|
30 Gy in 5 fractions |
89 |
|
|
20 Gy in 1 fractions |
|
MGH, Massachusetts General Hospital;
MDACC, M.D. Anderson Cancer Center.
aMegavoltage.
bOrthovoltage doses. For megavoltage, prescribe
dose to D90% or add 10% to total dose and prescribe to D |