RADIATION THERAPY ONCOLOGY GROUP RTOG 0418. A Phase II Study of Intensity Modulated Radiation Therapy (IMRT) to the Pelvis +/- Chemotherapy for Post-operative Patients with either Endometrial or Cervical Carcinoma

Endometrial cancer patients: IMRT 28 fractions over 5.5 weeks.
Cervical cancer patients: IMRT 28 fractions over 5.5 weeks and concurrent cisplatin starting on a Monday or a Tuesday for 5 weeks.

 Critical Structures (9/20/06)
Normal structures will be contoured using the full-bladder CT scan. Bladder – will be outlined on every slice, including the portion inferior to the planning target volume. Rectum – will be outlined on every slice, including the portion inferior to the planning target volume and superior to the level that it leaves the posterior pelvis around the region of the rectosigmoid. Small bowel – will be outlined on every slice, including at least 2 cm above the planning target volume. It includes the volume surrounding loops of small bowel out to the edge of the peritoneum because the bowel may lie within this space at any time throughout the course of treatment. The femoral heads and the sacrum should be contoured in all slices.

Participants are strongly encouraged to remain within these limits:

Small bowel < 30% to receive ≥ 40 Gy, minor deviation 30% to 40 Gy

Rectum < 60% to receive ≥ 30 Gy, minor deviation 35% to 50 Gy

Bladder < 35% to receive ≥ 45 Gy, minor deviation 35% to 50 Gy