| Dutch Colorectal
Cancer Group trial with 1,861 patients. Surgery was TME (total mesorectal
excision) and half were randomized to a short course of PreOp radiation (5
X 5Gy or 2500 cGy in 1 week.) They noted that the local relapse rate
as decrease from 22% previous surgery to 11.4% with TME surgery to 5.8%
with XRT and TME, though the survival in both arms was the same 64%) Marijnen . Onc News Int 2005 |
| Resection Margin | TME Alone | TME with preOp XRT |
| Positive | 23.3% | 15.5% |
| Negative | 9.1% | 3.7% |