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Bone Metastases:
the most common dose is 3000cGin 10 treatments of 300cGy over a two week period. For
patients with a large destructive lesion of a met to the spine, we sometimes go slower and
to a higher dose (e.g. 4000cGy in 20 treatments of 200cGy over a four week period. Brain Metastases: for patients with multiple brain metastases the most common protocol is to treat the whole brain to 3000cGy in 10 treatments of 300. For patients with 1 to 3 smaller lesions more aggressive approaches such as surgery or gamma knife treatment may be considered Brain Tumors: for glioblastoma
the usual dose is 5940cGy in 33 fractions of 180cGy or 6000cGy in 30 fractions. Low grade
gliomas generally get a slightly lower dose (5400cGy.) Colon/Rectum: the usual dose if 5040cGy in 28 fractions to the pelvis from four directions either before or after surgery. The radiation is usually combined with 5-FU chemotherapy Endometrial (Uterus): the usually postoperative dose if 4500 - 5040cGy in 28 fractions of 180cGy over 5 weeks. Some patients also receive HDR treatment (500cGy X 3) or may be treated entirely by HDR (500cGy X 5.) Esophagus: Most patients now are treated with combined radiation/chemotherapy. The radiation dose is generally 5040cGy - 5940cGy at 180cGy per fraction. Head & Neck: for early lesions, radiation alone 6600 - 7000cGy at 200cGy per fractions is common. For advanced disease this is combined with chemotherapy (e.g. Carboplatin/Taxol.) For postOp radiation the usual dose is 5940 to 6600cGy at 180cGy per fraction. Lung: most patients now receive concurrent chemotherapy (for small cell or non-small cell.) The usual radiation dose is 5940 to 6600 at 180-200cGy per fraction. Pancreas: radiation is usually combined with chemotherapy (5-FU or Gemzar) and the dose is 6000cGy at 200cGy per fraction. Prostate: for external beam alone the usual dose is 7500cGy at 180cGy per fraction for 40 treatments over 8 weeks. For combination we usually treat with external beam first (4500cGy at 180cGy) followed by an attenuated dose seed implant (11,500cGy for I-125 or 10,000cGy for Pd-103.) Skin: for small lesions 5100cGy at 300cGy in 17 fractions; for intermediate lesions 5500cGy at 250cGy in 22 fractions, for large lesions or very delicate skin 6000cGy at 200cGy in 30 fractions over 6weeks. |