Impact of targeting deviations on outcome in medulloblastoma: study of the French society of pediatric oncology (SFOP)1. Carrie IJROBP 1999;45:435

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Cranial target and required safety margin

posterior fossa limits

Supratentorial target
The entire brain must be covered with particular attention to the region of the cribriform plate and the temporal lobe region. The required safety margin below the orbital roof and the upper part of the orbital block (A) was 5 mm and between the posterior part of the orbital block and the lowest part of the temporal fossa 1 cm (B).


Posterior fossa volume

The anterior margin (C) was 0.5 cm in front of the clivus, the upper margin (D) was 1 cm above the midpoint between the intersection of the bisector with the superior and inferior skull . The posterior limit was a parallel line to the anterior margin through the torcular. The lower margin of the posterior fossa was 1 cm below the occipital foramen.

Spinal axis

Transverse vertebral processes must be included in totality in the field. The inferior aspect was 1 cm below the dural sac or at the level S2/S3, without a “spade-like” widening of the field inferiorly. The minimal spinal field width was 6 cm in case of electron beam therapy and 5 cm in case of photon beam. The dose prescription was calculated at the anterior aspect of the spinal cord for photon beam and at the maximum dose point for electron beam. The dose heterogeneity in the vertebral body must be less than 15%.