Stages of Endometrial Cancer (AJCC 7th Ed here)        Stage I - confined to the uterus                IA - lining only or less than 50% of myometrium                IB - 50% or deeper muscle                      Stage II - extending to include the stroma of the cervix        Stage III - spread further to the vagina,ovary                  IIIa - serosa or adnexa                  IIIb - vagina or parametrium                  IIIc1 - pelvic nodes                  IIIc2 - para-arotic nodes        Stage IV a - into bladder or rectum                  IVb - distant metastases      see more on older stage below and TNM stage here

Cancer of the Uterus makes up 6% of all female cancers but causes only 2% of all female cancer deaths, so it has a much better survival than other forms of cancer in women. The 5 year survival has improved from 1960 compared to 1990's, in white women from 73% to 86% and black women from 31% to 55%. For more survival data by stage go to , ACS

5 Year Survival by Stage or Grade

Stage	5 Year Survival	Grade	5 Year Survival
I	82%	1	87%
II	63%	2	75%
III	44%	3	57%
IV	17%

Survival in Stage I

Stage	5y Survival
IA	95%
IB	95%
IC	75%

5 Year Survival by SEER Stage (white women, 1989-1995 data)

Stage	Incidence	Survival
all	100%	86%
local	75%	96%
regional	13%	67%
distant	8%	28%

Details of the FIGO Staging System

-- Stage I -- Stage I endometrial cancer is carcinoma confined to the corpus uteri. stage IA: tumor limited to endometrium stage IB: invasion to less than one half of the myometrium stage IC: invasion to greater than one half of the myometrium -- Stage II -- Stage II endometrial cancer involves the corpus and the cervix, but has not extended outside the uterus. stage IIA: endocervical glandular involvement only stage IIB: cervical stromal invasion -- Stage III -- Stage III endometrial cancer extends outside of the uterus but is confined to the true pelvis. stage IIIA: tumor invades serosa and/or adnexa and/or positive peritoneal cytology stage IIIB: vaginal metastases stage IIIC: metastases to pelvic and/or para-aortic lymph nodes -- Stage IV -- Stage IV endometrial cancer involves the bladder or bowel mucosa or has metastasized to distant sites. stage IVA: tumor invasion of bladder and/or bowel mucosa stage IVB: distant metastases, including intra-abdominal and/or inguinal lymph nodes Grade Endometrial cancer can be grouped with regard to the degree of differentiation of the adenocarcinoma, as follows: G1: 5% or less of a nonsquamous or nonmorular solid growth pattern G2: 6% to 50% of a nonsquamous or nonmorular solid growth pattern G3: more than 50% of a nonsquamous or nonmorular solid growth pattern FIGO staging for endometrial cancer: Stage IA G123: tumor limited to endometrium Stage IB G123: invasion to less than one half the myometrium Stage IC G123: invasion to more than one half the myometrium Stage IIA G123: endocervical glandular involvement only Stage IIB G123: cervical stromal invasion Stage IIIA G123:tumor invades serosa and/or adnexa, and/or positiveperitoneal cytology Stage IIIB G123:vaginal metastases Stage IIIC G123:metastases of pelvic and/or para-aortic lymph nodes Stage IVA G123: tumor invasion of bladder and/or bowel mucosa Stage IVB: distant metastases including intra-abdominal and/or inguinal lymph nodes