Trials Comparing Lumpectomy with Mastectomy
Study Patients in Study Survival Lumpectomy Survival Mastectomy
NSABP 2105 62%/12y 62%/12
NCI 237 77%/10y 75%/10y
Gustav Roussy 179 79%/10y 80%/10y
NCI (Milan) 701 71%/13y 69%/13y
EORTC 902 71%/8y 73%/8y
Danish Breast 905 79%/6y 82%/6y
 

A Meta-analysis of 3,100 women from 7 randomized trials showed identical survival at 10 years (71%) (NEJM 1995;333:1444)

see summary table here

see 20 year data below (long term survival is identical whether the woman has a mastectomy or a lumpectomy)

       15 Year Survival Comparisons - NCI Trial
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Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer. NCI Trial


B. Fisher . NEJM 2002; 347:1233

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Twenty-Year Follow-up of a Randomized Study Comparing Breast-Conserving Surgery with Radical Mastectomy for Early Breast Cancer


U. Veronesi NEJM 2002; 347:1227.

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